RESEARCH & ARTICLES

No Association Between Donor Variables and Clinically Significant Outcomes, Reoperations, and Failure After Osteochondral Allograft Transplantation

Purpose: To determine whether donor factors-such as sex, age, donor-recipient sex mismatch, and graft storage duration-affect clinical outcomes or failure rates following knee osteochondral allograft transplantation. 

Summary: 

• This study looked at 372 patients undergoing OCA transplantation with a mean follow up of 5.4 years. 
• No differences in outcomes when considering donor-recipient sex mismatch, donor age or graft storage time (<28 days).

JRF Takeaways: JRF is dedicated to delivering OCAs that meet the unique needs and specifications of each surgeon. Findings from this long-term, single-center study indicate that factors such as donor-recipient sex mismatch and donor age do not significantly impact graft failure. Broadening certain criteria and specifications may ultimately allow for faster and more precise size-matching of OCAs, improving efficiency in the matching process. 

Click here for the complete abstract. 

Authors: Mario Hevesi, MD, PhD, Kyle R. Wagner, MD, Ryan A. Quigley, MD, Zach D. Meeker, BS, Allen A. Yazdi, BS, Alexander C. Weissman, BS, Sara A. Muth, BS, Nate S. Cohen, BS, Adam B. Yanke, MD, PhD, Brian J. Cole, MD, MBA

Published: The American Journal of Sports Medicine

Institution: Midwest Orthopaedics at Rush University Medical Center, Chicago, Illinois.